ONE (Optimal Nutritional Evaluation) FMV

ONE FMV nutritional test helps to give an understanding of individual diet and supplementation needs, and offers a personalized functional nutrition assessment covering Antioxidants, B Vitamins, Digestive Support, and Minerals.

Nutritional deficiencies can be a factor of many complex chronic conditions, and ONE FMV utilizes an easy first-morning urine collection (called a first morning void) to provide nutritional recommendations based on a patient’s individual nutritional test results. Clinicians commonly use such nutritional testing to determine the nutritional deficiencies that are at the root of chronic conditions.

Symptoms and chronic conditions related to nutritional deficiencies:

  • Mood disorders
    • Depression
    • Anxiety
    • Sleepdisturbance
  • Fibromyalgia
  • Fatigue
  • Optimized health and sports fitness

Using an easy-to-collect, first-morning urine sample, the ONE FMV nutritional test gives physicians a better understanding of patients’ diet and nutritional deficiencies. By combining testing in 4 key areas of core nutrients, physicians are offered a depth of insight into a patient’s overall nutritional status unrivaled in the laboratory industry. Genova Diagnostics has created an enhanced nutritional test report that synthesizes the results of nearly 80 individual biomarkers into one, easy-to-interpret overview, as well as a personalized patient supplementation schedule.

The ONE FMV Nutritional Test Covers:

  • MetabolicAnalysis Profile: Assessment provides information on 45 key organic acids. These biomarkers are grouped into easy-to-understand categories, and provide insight for functional support in the areas of: malabsorption & dysbiosis; cellularenergy & mitochondrial metabolism; neurotransmitter metabolism; vitamin deficiencies; and toxin exposure & detoxification need.
  • Amino Acids Analysis: Features either plasma (37 total) or urine (41 total) amino acids. This assesses nutritionally essential and non-essential amino acids, as well as intermediary metabolites that augment an understanding of B vitamin need, and need for support of protein digestion & absorption.
  • OxidativeStress: Biomarkers highlight the body’s current state of oxidative stress andreserve capacity. Markers of oxidative injury assess cell membrane (lipidperoxides) and DNA(8-hydroxydeguanosine/8-OHdG) damage, while direct measurement of glutathioneand CoQ10 provide insight into antioxidant reserve available to counterfree-radical impact. Additional markers are available in our Oxidative Stress 2.0 profile.

Test Type: Urine Test

Analyte List
1-Methylhistidine
2-Hydroxyphenylacetic Acid
3-Hydroxyproprionic Acid
3-Methyl-4-OH-phenylglycol
3-Methylhistidine
4-Hydroxyphenylpyruvic Acid
5-OH-Indoleacetic Acid
8-OHdG
Adipic Acid
Alanine
Alpha-amino-N-butyric acid
Alpha-aminoadipic acid
Ammonia
Anserine (dipeptide)
Arabinose
Arginine
Asparagine
Aspartic acid
Benzoic
Benzoic/Hippuric Acids Ratio
Beta-alanine
Beta-aminoisobutyric acid
Carnosine (dipeptide)
Cis-Aconitic Acid
Citramalic Acid
Citric Acid
Citrulline
Creatinine
Cystathionine
Cysteine
Cystine
Dihydroxyphenylpropionic Acid
Ethanolamine
Formiminoglutamic Acid (FIGlu)
Gamma-aminobutyric acid
Glucose
Glutamic acid
Glutamine
Glutaric Acid
Glycine
Hippuric
Histidine
Homogentisic Acid
Homovanillic Acid
Indoleacetic Acid
Isocitric Acid
Isoleucine
Kynurenic Acid
Lactic Acid
Leucine
Lipid Peroxides
Lysine
Malic Acid
Methionine
Methylmalonic Acid
Ornithine
Orotic Acid
Phenylacetic Acid
Phenylalanine
Phosphoethanolamine
Phosphoserine
Proline
Pyroglutamic Acid
Pyruvic Acid
Sarcosine
Serine
Suberic Acid
Succinic Acid
Taurine
Threonine
Tryptophan
Tyrosine
Urea
Valine
Vanilmandelic Acid
a-Keto-b-Methylvaleric Acid
a-Ketoadipic Acid
a-Ketoglutaric Acid
a-Ketoisocaproic Acid
a-Ketoisovaleric Acid
b-OH-Butyric Acid
b-OH-b-Methylglutaric Acid
CPT Codes  
1-Methylhistidine 82139
2-Hydroxyphenylacetic Acid 83921
3-Hydroxyproprionic Acid 83921
4-Hydroxyphenylpyruvic Acid 83921
5-OH-Indoleacetic Acid 83497
8-OHdG 83520
Adipic Acid 83921
Citric Acid 82507
Creatinine 82570
Glutaric Acid 83921
Homogentisic Acid 83921
Homovanillic Acid 83150
Isocitric Acid 83921
Lactic Acid 83605
Lipid Peroxides 84311
Malic Acid 83921
Methylmalonic Acid 83921
Orotic Acid 83921
Pyruvic Acid 84210
Suberic Acid 83921
Succinic Acid 83921
Vanilmandelic Acid 84585
a-Keto-b-Methylvaleric Acid 83921
a-Ketoadipic Acid 83921
a-Ketoglutaric Acid 83921
a-Ketoisocaproic Acid 83921
a-Ketoisovaleric Acid 83921
b-OH-Butyric Acid 83921
b-OH-b-Methylglutaric Acid 83921
Specimen Requirements
1 green-top preservative tube - FMV urine (frozen); 1 blue-top amber tube - FMV urine (frozen); 1 green-top tube - FMV urine (frozen)