Essential & Metabolic Fatty Acids Analysis (EMFA)

Assess the Balance between Critical Fatty Acids

Proceed to Clinical Overview

Why use the Essential & Metabolic Fatty Acids Analysis?

The Essential & Metabolic Fatty Acids Analysis (EMFA) assesses the critical balance between essential Omega-6/Omega-3 fatty acids, as well as additional key fatty acids important in metabolism and cellular function. Fatty acid imbalances can be a causative factor in a variety of chronic health conditions. The Essential and Metabolic Fatty Acids Analysis can indicate the need for fatty acid supplementation and/or dietary modification.

Effective for Patients Experiencing:

Essential and Metabolic Fatty Acids Analysis is useful for patient concerns including:

  • Chronic Pain/Inflammatory Conditions
  • Depression
  • Cardiovascular Risk
  • Weight Issues/Dietary Guidance

About the Essential & Metabolic Fatty Acids Analysis

The complete EMFA provides a red blood cell analysis of:

  • Omega 3 Fatty Acids
  • Omega 6 Fatty Acids
  • Omega 9 Fatty Acids
  • Saturated Fatty Acids
  • Monounsaturated Fats
  • Delta-6 Desaturase Activity
  • Cardiovascular Risk Ratios

The EMFA report provides:

  • Colorimetric reporting of results &ndash allows quick determination of potential areas of concern
  • Essential Fatty Acid Metabolism Infographic &ndash provides listings of cofactor nutrients associated with key enzymes involved in essential fatty acid metabolism

Clinical Overview

What is the Essential & Metabolic Fatty Acid Analysis (EMFA)?

Fatty acids are the core building blocks of cellular membranes making them critical for cell membrane structure and function as well as local signaling. Essential fatty acids (EFAs) cannot be synthesized by the human body and must be obtained in the diet or through supplementation. EFAs are transformed into local hormonal mediators called eicosanoids, a process vital in the ability of the body's immune system to repair and protect itself and to regulate inflammation. The Essential and Metabolic Fatty Acids Analysis evaluates the levels of essential and non-essential red blood cell membrane fatty acids, imbalances of which significantly impact cellular functions, intracellular communication, and neurological/brain development.

When Should an EMFA be Considered?

Evaluating Essential and Metabolic Fatty Acids can be helpful for patients with inflammatory disorders, cardiovascular issues, hormonal disorders, autoimmune disorders, arthridities, senile neurological degeneration, mental and behavioral disorders, attention deficit hyperactivity disorder (ADHD), insulin resistance and obesity, and hair and skin related conditions.

What Advantage Does the EMFA Offer Compared to Other Diagnostics?

The conventional approach to fatty acid-related symptoms or conditions does not routinely include utilization of comprehensive fatty acid evaluation. When testing is performed, a few select polyunsaturated fatty acids (Omega 3 and 6) are typically evaluated to determine candidates for supplementation therapy. In contrast, the comprehensive EMFA profile includes:

  • Omega 3 Fatty Acids
  • Omega 6 Fatty Acids
  • Omega 9 Fatty Acids
  • Saturated Fatty Acids
  • Monounsaturated Fats
    • Omega 7 Fats
    • Trans Fat

  • Delta-6 Desaturase Activity
    • Linoleic/DGLA Ratio

  • Cardiovascular Risk Ratios
    • Omega 6/Omega 3 Ratio
    • AA/EPA Ratio
    • Omega 3 Index

The unique EMFA report provides:

  • Colorimetric reporting of results &ndash allows clinicians to quickly determine potential areas of concern
  • Essential Fatty Acid Metabolism Infographic &ndash provides listings of cofactor nutrients required by key enzymes involved in EFA elongation and desaturation

What Can Clinicians and Patients Expect from EMFA Testing?

Essential and Metabolic Fatty Acids testing can indicate the need for fatty acid supplementation and dietary modification. Clinically significant fatty acid imbalances are precisely identified on a clear, easy-to interpret test report that serves as the foundation for designing an effective, customized dietary and supplementation program to support fatty acid sufficiency and balance.

Analyte List
Arachidic
Arachidonic
Behenic
Dihomo-gamma-linolenic
Docosahexaenoic
Docosapentaenoic
Docosatetraenoic
Eicosadienoic
Eicosapentaenoic
Elaidic
Gamma-Linolenic
Gondoic
Lignoceric
Linoleic
Margaric
Nervonic
Oleic
Palmitic
Palmitoleic
Pentadecanoic
Stearic
Tricosanoic
Vaccenic
alpha-Linolenic
CPT Codes  
Arachidic 82542
Behenic 82726
Docosatetraenoic 82726
Lignoceric 82726
Nervonic 82726
Tricosanoic 82726
Specimen Requirements
2 EDTA tubes each of 6ml whole blood