Amino Acids Analysis, Plasma

A Nutritional Assay for Personalized Supplementation

Featuring Plasma Amino Acids

Proceed to Clinical Overview

Why use Amino Acid Analysis, Plasma Profile?

The Amino Acid Analysis, Plasma measures levels of key amino acids in blood. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of amino acids. Plasma amino acid analysis is favored in conditions where the supply of amino acids and precursors is critical, such as in mood and neurobehavioral disorders.

Effective for Patients Experiencing:

Clinical indications for testing include:

  • Mood Disorders
  • Weight Issues/Dietary Guidance
  • Dietary Issues Related to Protein Intake and Digestion

About the Amino Acid Analysis, Plasma

The complete Amino Acid Analysis, Plasma analyzes over 40 analytes and includes:

  • Plasma Amino Acid Analysis
    • Nutritionally Essential Amino Acids
    • Nonessential Protein Amino Acids
    • Intermediary Metabolites
    • Dietary Peptide Related Markers

The Amino Acid Analysis, Plasma report configuration provides for easy interpretation and clinically actionable results and includes:

  • A handy Suggested Supplement Schedule allowing for personalized recommendations based on test results
  • An Interpretation-At-A-Glance page that provides facts on nutrient function, causes and complications of their deficiencies, as well as dietary sources


Clinical Overview

What is the Amino Acid Analysis, Plasma?

Amino acids play central roles as building blocks of proteins and as intermediates in metabolism. Amino acid metabolism may be compromised by common lifestyle and dietary factors, which may result in inadequate levels of essential amino acids and/or missing nutrient cofactors required for effective amino acid metabolism. Intervention with amino-acid supplementation and nutrient cofactors may also be effective in conditions associated with inefficient amino acid metabolism.

Genova's Amino Acid Analysis in plasma measures levels of key amino acids in blood. Measuring amino acids in a fasting plasma sample provides a measurement of the overall "steady-state" amino acid pool. The test identifies amino-acid insufficiencies and imbalances, which can occur due to inadequate dietary intake and/or maldigestion/malabsorption of dietary proteins.

The complete Amino Acid Analysis, Plasma offers:

  • Nutritionally Essential Amino Acids (11 analytes)
  • Nonessential Protein Amino Acids (9 analytes)
  • Intermediary Metabolites (14 analytes)
  • Dietary Peptide Related Markers
    • B-Vitamin Markers
    • Urea Cycle Markers
    • Glycine/Serine Metabolites
  • Dietary-Peptide Related Markers (2 analytes)

The Amino Acid Analysis, Plasma report provides for easy interpretation and enhanced clinical utility:

  • Synthesized results and actionable areas of high need for supplementation:
    • Results Overview Cover Page – provides the busy clinician with an immediate sense of patient areas requiring focus
    • Suggested Supplement Schedule – provides personalized recommendations for antioxidants, B-vitamins, minerals, digestive support, and amino acids
    • Interpretation At-A-Glance – provides patients with valuable information about the function of individual nutrients, causes and complications of their deficiencies, and their dietary sources

When Should the Amino Acid Analysis, Plasma be Considered?

Clinical indications for testing include:

  • Mood Disorders
  • Weight Issues/Dietary Guidance
  • Gaining insight into Dietary Protein Intake and Digestion/Absorption

The plasma amino acid measurements in the Amino Acid Plasma profile represent the steady state of the body's amino acid pool. Plasma samples are preferred when assessing clinical conditions for which amino acid supplementation may be indicated (such as neuropsychiatric or behavioral disorders), or in states of lowered immune function or questionable dietary protein intake. Consider using plasma amino acids in patients who have inconsistent diets and are unable to maintain a controlled dietary intake (i.e. eating disorders, chronically ill patients, cancer patients). Plasma amino acids are also recommended for individuals with proteinuria, since urinary amino acid levels will be affected in this condition.

What Advantage Does the Profile Offer Compared to Other Diagnostics?

Amino acid assessment can provide guidelines for dietary modification of protein intake and can indicate the functional need for:

  • Specific amino acid supplementation
  • Digestive support
  • Nutrient cofactors (antioxidants, B-vitamins, minerals)

An Interpretation-At-A-Glance section provides information on each recommended nutrient including nutrient function, possible causes of deficiency, complications of deficiency, and food sources. In addition, a supplementation schedule is provided, offering suggested replacement amounts based on test results.

What Can Clinicians and Patients Expect from Amino Acid Analysis, Plasma Testing?

Imbalanced or insufficient amino acids can affect a wide range of body functions, producing symptoms that negatively affect the quality of life. A targeted nutritional assessment panel Ð such as the Amino Acid Analysis, Plasma profile Ðprovides clinical utility and supports the development of personalized treatments. Identification and targeted treatment of underlying imbalances with customized nutrient recommendations can enhance other treatments and increase the patients' overall health and ability to combat chronic illness.

Also available:

  • Amino Acid Analysis, Urine – offers the amino acid assay in urine; most useful for assessing vitamin/mineral cofactors that affect amino acid metabolism

Test Type: Plasma Test

Analyte List
1-Methylhistidine
3-Methylhistidine
Alanine
Alpha-amino-N-butyric acid
Alpha-aminoadipic acid
Anserine (dipeptide)
Arginine
Argininosuccinic acid
Asparagine
Aspartic acid
Beta-alanine
Beta-aminoisobutyric acid
Carnosine (dipeptide)
Citrulline
Cyst(e)ine
Cystathionine
Ethanolamine
Gamma-aminobutyric acid
Glutamic acid
Glutamine
Glycine
Histidine
Homocysteine
Hydroxyproline
Isoleucine
Leucine
Lysine
Methionine
Ornithine
Phenylalanine
Phosphoethanolamine
Phosphoserine
Proline
Sarcosine
Serine
Taurine
Threonine
Tryptophan
Tyrosine
Urea
Valine
CPT Codes  
1-Methylhistidine 82139
Specimen Requirements
2ml plasma (preserved with sulfosalicylic acid)